Bilateral Lesions in the Posterior Limb of Internal Capsule Attributed to Combination Therapy of Isoniazid and Rifampin
Journal of the Korean Neurological Association
; : 354-357, 2018.
Article
in Ko
| WPRIM
| ID: wpr-766713
Responsible library:
WPRO
ABSTRACT
Transient isoniazid-induced brain lesions have rarely been reported. The lesions were in the dentate nucleus of cerebellum and thalamus. Meanwhile, the neurotoxicity of rifampin has not been reported evidently. We observed bilateral lesions in the internal capsule in a young woman after taking a combination of isoniazid and rifampin. She transiently suffered numbness in both hands, dysarthria, and left side motor weakness while taking the medication. Isoniazid may induce structural lesions in various brain areas including the internal capsule.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Rifampin
/
Thalamus
/
Brain
/
Cerebellar Nuclei
/
Cerebellum
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Internal Capsule
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Neurotoxicity Syndromes
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Dysarthria
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Extremities
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Hand
Limits:
Female
/
Humans
Language:
Ko
Journal:
Journal of the Korean Neurological Association
Year:
2018
Type:
Article