Research Progress of m6A-Methylation in Acute Leukemia-Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 2014-2018, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-781502
ABSTRACT
Epigenetic abnormalities play an important role in the pathogenesis of hematological malignancies, especially acute leukemia (AL). Similar to DNA methylation and histone modifications, RNA methylation is another important epigenetic modification. m6A methylation is one of the most prevalent and extensively studied RNA methylation. m6A methylation is involved in many biological and pathological process. Recent studies have found that m6A methylation is involved in the occurrence, development and drug-resistance of AL. This review focuses on the research progress of m6A methylation in AL.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Leukemia
/
DNA Methylation
/
Epigenesis, Genetic
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2019
Type:
Article
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