Risk factors for cow's milk protein allergy in infants: a multicenter survey / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 42-46, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-781697
ABSTRACT
OBJECTIVE@#To investigate the risk factors for cow's milk protein allergy (CMPA) among infants through a multicenter clinical study.@*METHODS@#A total of 1 829 infants, aged 1-12 months, who attended the outpatient service of the pediatric department in six hospitals in Shenzhen, China from June 2016 to May 2017 were enrolled as subjects. A questionnaire survey was performed to screen out suspected cases of CMPA. Food avoidance and oral food challenge tests were used to make a confirmed diagnosis of CMPA CMPA. A multivariate logistic regression analysis was used to investigate the risk factors for CMPA.@*RESULTS@#Among the 1 829 infants, 82 (4.48%) were diagnosed with CMPA. The multivariate logistic regression analysis showed that maternal food allergy (OR=4.91, 95%CI 2.24-10.76, P6 months (OR=0.38, 95%CI 0.17-0.86, P<0.05) were protective factors.@*CONCLUSIONS@#The introduction of complementary food at an age of <4 months, maternal food allergy, and antibiotic exposure during pregnancy are risk factors for CMPA in infants.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
China
/
Surveys and Questionnaires
/
Risk Factors
/
Milk Hypersensitivity
/
Milk Proteins
Type of study:
Controlled clinical trial
/
Etiology study
/
Risk factors
Limits:
Animals
/
Female
/
Humans
/
Pregnancy
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2020
Type:
Article
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