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Dietary and modifiable factors contributing to hyper-LDL-cholesterolemia prevalence in nationwide time series data and the implications for primary prevention strategies
Nutrition Research and Practice ; : 62-69, 2020.
Article in English | WPRIM | ID: wpr-782256
ABSTRACT
OBJECTIVES: A number of studies examined secular trends in blood lipid profiles using time series data of national surveys whereas few studies investigated individual-level factors contributing to such trends. The present study aimed to examine secular trends in dietary and modifiable factors and hyper-LDL-cholesterolemia (HC) prevalence and evaluate their associations using time series data of nationwide surveys.SUBJECTS/

METHODS:

The study included 41,073 Korean adults aged ≥ 30 years from the 2005, 2007–2009, 2010–2012, 2013–2015, and 2016 Korea National Health and Nutrition Examination Surveys. Stepwise logistic regression analysis was performed to select significant factors associated with HC, which was defined as serum LDL cholesterol levels ≥130 mg/dL.

RESULTS:

The following factors showed a positive association with HC (P < 0.05) for men having higher body mass index (BMI), being married, having an office job, and consuming higher dairy and vegetable oil products; for women having higher age or BMI, having no job or a non-office job, not in a low-income household, and consuming higher dairy products. In the given model, the 2016 survey data showed that a 2 kg/m² reduction in BMI of obese persons resulted in a decreased HC prevalence from 30.8% to 29.3% among men and from 33.6% to 32.5% among women.

CONCLUSIONS:

Based on these findings, it is suggested that primary prevention programs should advocate having proper BMI for Korean adults with a high-risk of HC. However, whether discouraging consumption of dairy and vegetable oil products can reduce HC prevalence warrants further studies with a prospective longitudinal design.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Primary Prevention / Vegetables / Body Mass Index / Logistic Models / Family Characteristics / Cholesterol / Prevalence / Prospective Studies / Dairy Products / Korea Type of study: Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Nutrition Research and Practice Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Primary Prevention / Vegetables / Body Mass Index / Logistic Models / Family Characteristics / Cholesterol / Prevalence / Prospective Studies / Dairy Products / Korea Type of study: Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Nutrition Research and Practice Year: 2020 Type: Article