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Significance of Decreasing Rate of HIV and HBV Co-infection in a Nationwide Korean HIV/AIDS Cohort
Journal of Korean Medical Science ; : 7-2020.
Article in English | WPRIM | ID: wpr-782497
ABSTRACT
human immunodeficiency virus (HIV) individuals < 70 years enrolled in Korea human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) cohort were analyzed to investigate the prevalence of HIV/HBV co-infection rate and hepatitis B virus surface antibody (HBsAb) positive rate based on birth year. The HBV co-infection prevalence rate was the highest (8.8%) in patients born between 1960 and 1964 and the lowest (0%) among those born between 1995 and 1999. A decreasing linear trend of HBV co-infection rate was observed according to the 5-year interval changes. HBsAb-positive rate was only 58.1% in our study. The national HBV vaccination programs have effectively lowered the HBV co-infection rate in HIV population. However, it is identified that the HIV population has low HBsAb positive rate. Further evidences supporting efficacy of booster immunization for HBsAb negative HIV patients are required and efforts should be made to increase HBsAb positive rates among HIV patients to prevent horizontal transmission.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: HIV Infections / Hepatitis B virus / Prevalence / Cohort Studies / HIV / Immunization, Secondary / Vaccination / Parturition / Coinfection / Korea Type of study: Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Humans Country/Region as subject: Asia Language: English Journal: Journal of Korean Medical Science Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: HIV Infections / Hepatitis B virus / Prevalence / Cohort Studies / HIV / Immunization, Secondary / Vaccination / Parturition / Coinfection / Korea Type of study: Etiology study / Incidence study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Humans Country/Region as subject: Asia Language: English Journal: Journal of Korean Medical Science Year: 2020 Type: Article