Gastric Adenocarcinoma Secondary to Primary Gastric Diffuse Large B-cell Lymphoma
Journal of Gastric Cancer
; : 180-185, 2017.
Article
in En
| WPRIM
| ID: wpr-80094
Responsible library:
WPRO
ABSTRACT
Despite the decreasing incidence and mortality from gastric cancer, it remains a major health problem worldwide. Ninety percent of cases are adenocarcinomas. Here, we report a case of gastric adenocarcinoma developed after successful treatment of prior primary gastric diffuse large B-cell lymphoma (DLBCL). Our patient was an elderly man with primary gastric DLBCL in whom complete remission was achieved after R-CHOP (cyclophosphamide, adriamycin, vincristine, prednisolone plus rituximab) chemotherapy. Helicobacter pylori infection persisted despite adequate treatment leading to sustained chronic gastritis. The mean time to diagnose metachronous gastric carcinoma was seven years. We believe that a combination of many risk factors, of which chronic H. pylori infection the most important, led to the development of gastric carcinoma following primary gastric lymphoma. In summary, patients who have been successfully treated for primary gastric lymphoma should be followed up at regular short intervals. H. pylori infection should be diagnosed promptly and treated aggressively.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Stomach Neoplasms
/
Vincristine
/
Prednisolone
/
B-Lymphocytes
/
Adenocarcinoma
/
Doxorubicin
/
Incidence
/
Risk Factors
/
Mortality
/
Lymphoma, B-Cell
Type of study:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Humans
Language:
En
Journal:
Journal of Gastric Cancer
Year:
2017
Type:
Article