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Application of alkaloids in reversing multidrug resistance in human cancers / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.) ; (6): 561-571, 2018.
Article in English | WPRIM | ID: wpr-812374
ABSTRACT
Multidrug resistance (MDR) in human cancer is one of greatest challenges in cancer therapy. Natural products, especially the alkaloids, exert reversed effects on MDR with low toxicity, by interacting with various targets. In this review article, we summarize the recent progress made in the research of the main alkaloids, including classification, function, mechanism, research status, and application in reversing MDR.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Biological Products / Chemistry / Drug Resistance, Multiple / Drug Resistance, Neoplasm / Drug Antagonism / Drug Therapy / Alkaloids / Neoplasms Limits: Animals / Humans Language: English Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Biological Products / Chemistry / Drug Resistance, Multiple / Drug Resistance, Neoplasm / Drug Antagonism / Drug Therapy / Alkaloids / Neoplasms Limits: Animals / Humans Language: English Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2018 Type: Article