Epigenetic research progress in colorectal cancer / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 830-836, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-813229
ABSTRACT
Colorectal cancer is one of the common malignant tumors, which seriously threatens human health. Its morbidity and mortality rank the third and the second among all malignant tumors. The progress of colorectal cancer is a complex process involving the accumulation of genetic and epigenetic changes. Epigenetic changes of colorectal cancer mainly include DNA methylation, histone modification, non-coding RNAs (such as microRNAs and lncRNAs), which are of great significance to early diagnosis and prognosis evaluation, and to chemosensitivity assessment for colorectal cancer, providing a new thought for the treatment of colorectal cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Histones
/
Colorectal Neoplasms
/
DNA Methylation
/
Epigenesis, Genetic
/
Epigenomics
/
Genetics
Type of study:
Screening study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2019
Type:
Article
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