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Efficacy and mechanism of electroacupuncture on insulin resistant polycystic ovary syndrome / 中国针灸
Chinese Acupuncture & Moxibustion ; (12): 379-383, 2020.
Article in Chinese | WPRIM | ID: wpr-826726
ABSTRACT
OBJECTIVE@#To explore the therapeutic effect and partial mechanism of electroacupuncture (EA) for patients with insulin resistance (IR) polycystic ovary syndrome (PCOS).@*METHODS@#Seventy patients with IR-PCOS were randomly divided into an EA group (36 cases, 5 cases dropped off) and a medication group (34 cases, 4 cases dropped off). The patients in the medication group were treated with oral administration of metformin hydrochloride, 500 mg each time, twice a day. The patients in the EA group were treated with EA (continuous wave, 2 Hz of frequency) at Zusanli (ST 36), Zhongwan (CV 12), Qihai (CV 6), Yishu (EX-B 3), Shenshu (BL 23), Pishu (BL 20), Ciliao (BL 32) for 30 min, three times a week. One menstrual cycle or 4 weeks were taken as a course of treatment, and 3 continuous courses were given. The follow-up was 3 months. The lipid metabolism indexes of triacylglycerol (TG), total cholesterol (TC), high-density lipoprotein (HDL) and low-density lipoprotein (LDL), homeostasis model assessment-insulin resistance index (HOMA-IR) and testosterone (T) in serum were compared before and after treatment, and the clinical effects of the two groups were evaluated during the follow-up.@*RESULTS@#The total effective rate was 67.7% (21/31) in the EA group and 60.0% (18/30) in the medication group, with no significant difference between the two groups (>0.05). After treatment, the levels of serum T, HOMA-IR, LDL, TG and TC were decreased significantly in the two groups (<0.01, <0.05), and HDL was increased significantly (<0.01); the levels of TC in the EA group after treatment was lower than that in the medication group (<0.05).@*CONCLUSION@#EA may adjust some dyslipidemia in patients to correct IR and improve endocrine disorder of PCOS, which had superior/similar effects to metformin.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Polycystic Ovary Syndrome / Therapeutics / Insulin Resistance / Acupuncture Points / Electroacupuncture Limits: Female / Humans Language: Chinese Journal: Chinese Acupuncture & Moxibustion Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Polycystic Ovary Syndrome / Therapeutics / Insulin Resistance / Acupuncture Points / Electroacupuncture Limits: Female / Humans Language: Chinese Journal: Chinese Acupuncture & Moxibustion Year: 2020 Type: Article