The Effect of the Spinal Block Level on the Requirements of Propofol for Sedation / 대한마취과학회지
Korean Journal of Anesthesiology
; : 642-645, 2006.
Article
in Ko
| WPRIM
| ID: wpr-85126
Responsible library:
WPRO
ABSTRACT
BACKGROUND: It has been reported that spinal anesthesia has a sedative effect and so this decreases the hypnotic requirement of intravenous anesthetic. Therefore, we have conducted a prospective randomized study to investigate the effect of the spinal anesthesia level on the hypnotic requirements for conscious sedation. METHODS: Forty adult patients were scheduled to undergo spinal anesthesia, and they were randomly allocated to one of the two groups. After subarachnoid injection of 0.5% hyperbaric bupivacaine 16 mg, the patients in group 1 and group 2 were maintained in a reversed Trendelenburg position and a Trendelenburg position, respectively. After fifteen minutes, the target controlled infusion of propofol was started for achieving a target concentration of 1 microgram/ml, and the mean BIS for 1 min was checked after an effect site concentration (Ce) of 1 microgram/ml was reached. The target controlled infusion of propofol was restarted at a target concentration (Tc) of 1.5 microgram/ml, and the mean BIS for 1 min was checked after the Ce level of 1.5 microgram/ml was reached. RESULTS: The mean BIS at 1 microgram/ml Ce was 90.0 +/- 8.5 and 77.8 +/- 10.3 in group 1 and group 2, respectively. The mean BIS at 1.5 g/ml Ce was 73.6 +/- 19.4 and 60.0 +/- 13.1, respectively. CONCLUSIONS: There was a significant difference in the requirements of propofol for conscious sedation between the below T12 block group and the above T4 block group.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Bupivacaine
/
Propofol
/
Prospective Studies
/
Conscious Sedation
/
Head-Down Tilt
/
Hypnosis
/
Hypnotics and Sedatives
/
Anesthesia, Spinal
Type of study:
Clinical_trials
/
Observational_studies
Limits:
Adult
/
Humans
Language:
Ko
Journal:
Korean Journal of Anesthesiology
Year:
2006
Type:
Article