Chemical constituents from leaves of Adinandra nitida (II) / 中草药

ABSTRACT

Objective: To study the chemical constituents from the ethyl acetate extract of the leaves of Adinandra nitida. Methods: Several column chromatography including silica gel, Sephadex LH-20 gel, and ODS were applied in isolation and purification. The structures were elucidated on the basis of physicochemical properties and spectral data from 1H-NMR, 13C-NMR, ESI-MS and so on. Results: Nine flavonoids, three phenolic acids, and two other compounds were isolated and determined as apigenin (1), naringenin (2), luteolin (3), chrysoeriol (4), (-)-epicatechin (5), quercetin (6), quercitrin (7), camellianin A (8), camellianin B (9), p-methoxyphenol (10), protocatechuic acid (11), 3,3',4,4'-tetrahydroxybiphenyl (12), scopoletin (13), and palmitic acid (14). Conclusion: Compounds 3, 10-14 are firstly isolated from the plant of A. nitida and compounds 3, 10, 12, and 13 are obtained from Theaceae for the first time.