Effect of Pentoxifylline on the ICSI Program Undergone in Severe Asthenozoospermia / 대한불임학회지
Korean Journal of Fertility and Sterility
; : 97-103, 2002.
Article
in Ko
| WPRIM
| ID: wpr-8617
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: The aim of this study was to evaluate the effect of Pentoxifylline(PF) on the conventional ICSI program undergone in severe asthenozoospermia. METHOD: Total 348 cycles of ICSI programs undertaken at CHA General Hospital from January, 1996 to September, 2000, were divided into two groups - injected with pentoxifylline-treated sperm(PFT, 204 cycles) or non-treated sperm(NPFT, 144 cycles) and the clinical results of PFT group were compared with those of NPFT. RESULTS: PF-treatment on sperm increased their motility of normozoospermia and severe asthenozoospermia. Fertilization rate of PFT group was higher than those of ICSI programs undertaken using sperm of NPFT(70.6% vs. 62.9%, p<0.01). And, ET and clinical pregnancy rates of PFT were slightly higher than those of NPFT(93.1%, 44.2% vs. 90.3%, 36.2%). CONCLUSION: These results showed that treatment of pentoxifylline has a beneficial role on selection of viable sperm in severe asthenozoospermia.
Full text:
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Index:
WPRIM
Main subject:
Pentoxifylline
/
Spermatozoa
/
Pregnancy Rate
/
Sperm Injections, Intracytoplasmic
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Asthenozoospermia
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Fertilization
/
Hospitals, General
Language:
Ko
Journal:
Korean Journal of Fertility and Sterility
Year:
2002
Type:
Article