Comparative Results of Trabeculectomy with Mitomycin C in Uveitic Glaucoma versus Primary Open-Angle Glaucoma
Journal of the Korean Ophthalmological Society
; : 1408-1415, 2015.
Article
in Ko
| WPRIM
| ID: wpr-86780
Responsible library:
WPRO
ABSTRACT
PURPOSE: In this study we evaluated the long-term outcomes and prognostic factors of trabeculectomy with mitomycin C (MMC) in eyes with uveitic glaucoma (UG) compared with primary open-angle glaucoma (POAG). METHODS: We performed a retrospective chart review of 60 eyes with UG and 402 eyes with POAG that were followed up for at least 1 year after trabeculectomy with MMC between June 2000 and December 2012. The review included intraocular pressure (IOP), number of anti-glaucoma medications, and postoperative complications. Surgical success was analyzed using the Kaplan-Meier life-table method based on 2 definitions of successful IOP control with topical anti-glaucoma medications: Definition A (IOP < or = 15 mm Hg) and Definition B (IOP < or = 18 mm Hg). Risk factors for surgical failure of trabeculectomy were analyzed using the Cox proportional hazards model. RESULTS: Success rate at 5 years after trabeculectomy was lower in UG than in POAG (65.8% vs. 76.4%, Definition B), but without significant difference. However, UG had a significantly lower cumulative probability of success than POAG based on Kaplan-Meier survival curves (p = 0.049 and 0.044, respectively). Postoperative hypotony and hypotony maculopathy was more frequent in UG (p = 0.044 and 0.044, respectively). In UG, the Cox proportional hazards model showed postoperative shallow anterior chamber was associated with surgical failure in both Definition A and B. CONCLUSIONS: Long-term results of trabeculectomy with MMC in eyes with UG showed successful IOP control similar to POAG. Trabeculectomy with MMC is a reasonable surgical option for the management of UG.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Postoperative Complications
/
Trabeculectomy
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Proportional Hazards Models
/
Glaucoma
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Glaucoma, Open-Angle
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Retrospective Studies
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Risk Factors
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Mitomycin
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Kaplan-Meier Estimate
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Intraocular Pressure
Type of study:
Etiology_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Language:
Ko
Journal:
Journal of the Korean Ophthalmological Society
Year:
2015
Type:
Article