The emerging role of mitochondrial dysfunction in the pathogenesis and treatment of diabetic complications / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 161-164, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-870000
ABSTRACT
Mitochondrial dysfunction plays an important role in the pathogenesis of diabetic complications, and more attention has been paid to the treatment strategies targeting mitochondrial function in these diseases. Our group has been devoted to exploring the relationship between mitochondrial dysfunction such as mitochondrial oxidative stress and energy metabolism, as well as various diabetic complications. This review highlighted recent progresses in the role of mitochondrial dysfunction in the pathogenesis of diabetic ulcer, diabetic nephropathy, diabetes complicated with nonalcoholic fatty liver and their correspondent molecular pathways, tried to explore the feasibility of targeting mitochondrial dysfunction in the treatment of these diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2020
Type:
Article
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