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Prognostic implication of systemic inflammatory markers in young patients with resectable colorectal cancer
Annals of Surgical Treatment and Research ; : 25-32, 2021.
Article in English | WPRIM | ID: wpr-874214
ABSTRACT
Purpose@#The prognosis of young colorectal cancer (CRC) patients has not fully been addressed. The prognostic significance of systemic inflammatory markers was examined in those patients. @*Methods@#A total of 965 patients with resectable CRC were divided into young (≤ 50 years, n = 101) and old groups (>51 years, n = 864). Neutrophil-to-lymphocyte ratio (NLR) > 5, derived NLR (dNLR) > 3, lymphocyte-to-monocyte ratio (LMR) 150, and prognostic nutritional index (PNI) 5, LMR 3 and those markers showed significance for PFS. LMR 150 (HR, 1.45; P = 0.036) and PNI < 45 (HR, 1.73; P = 0.002) were significant markers for PFS. @*Conclusion@#Systemic inflammation might be one of biologic factors that influence on prognosis of young CRC.
Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: English Journal: Annals of Surgical Treatment and Research Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: English Journal: Annals of Surgical Treatment and Research Year: 2021 Type: Article