Short-chain fatty acid butyrate acid attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice and the underlying mechanism

Hong-Bo BAI; Ping YANG; Han-Bin ZHANG; Yu-Lin LIU; Shu-Xiang FANG; Xiao-Yang XU

Short-chain fatty acid butyrate acid attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice and the underlying mechanism / 生理学报

Hong-Bo BAI; Ping YANG; Han-Bin ZHANG; Yu-Lin LIU; Shu-Xiang FANG; Xiao-Yang XU.

Acta Physiologica Sinica ; (6): 42-50, 2021.

Article in Chinese | WPRIM | ID: wpr-878234

ABSTRACT

ABSTRACT

This study was designed to evaluate the role of short-chain fatty acid butyrate acid on intestinal morphology and function, and atherosclerotic plaque formation in apolipoprotein E-knockout (ApoE

Subject(s)

Animals; Humans; Mice; Apolipoproteins E/genetics; Atherosclerosis/prevention & control; Butyrates/pharmacology; Caco-2 Cells; Diet, High-Fat/adverse effects; Fatty Acids, Volatile; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Apolipoproteins E / Butyrates / Mice, Knockout / Caco-2 Cells / Atherosclerosis / Fatty Acids, Volatile / Plaque, Atherosclerotic / Diet, High-Fat / Mice, Inbred C57BL Limits: Animals / Humans Language: Chinese Journal: Acta Physiologica Sinica Year: 2021 Type: Article

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