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Advances in molecular mechanisms of bone invasion by oral cancer / 华西口腔医学杂志
West China Journal of Stomatology ; (6): 221-226, 2021.
Article in Chinese | WPRIM | ID: wpr-878434
ABSTRACT
Bone invasion by oral cancer is a common clinical problem, which affects the choice of treatment and predicts a poor prognosis. Unfortunately, the molecular mechanism of this phenomenon has not been fully elucidated. Current studies have revealed that oral cancer cells modulate the formation and function of osteoclasts through the expression of a series of signal molecules. Many signal pathways are involved in this process, of which receptor activator of nuclear factor-κB ligand/receptor activator of nuclear factor-κB/osteoprotegerin signaling pathway attracted much attention. In this review, we introduce recent progress in molecular mechanisms of bone invasion by oral cancer.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoclasts / Bone and Bones / Bone Resorption / Mouth Neoplasms / RANK Ligand / Receptor Activator of Nuclear Factor-kappa B / Osteoprotegerin Type of study: Prognostic study Limits: Humans Language: Chinese Journal: West China Journal of Stomatology Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoclasts / Bone and Bones / Bone Resorption / Mouth Neoplasms / RANK Ligand / Receptor Activator of Nuclear Factor-kappa B / Osteoprotegerin Type of study: Prognostic study Limits: Humans Language: Chinese Journal: West China Journal of Stomatology Year: 2021 Type: Article