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Research progress on the correlation between abnormal sperm DNA methylation and semen quality / 中华医学遗传学杂志
Chinese Journal of Medical Genetics ; (6): 188-193, 2021.
Article in Chinese | WPRIM | ID: wpr-879553
ABSTRACT
DNA methylation as an important aspect of epigenetics plays an important role in spermatogenesis and embryonic development. In recent years, researchers have found that male infertility, in particular abnormal semen quality, is related to abnormal DNA methylation. To further delineate the pathogenesis of male infertility and inspire new ideas for the treatment of male infertility, a comprehensive review over the correlation between abnormal methylation of imprinted genes, repetitive DNA elements and non-imprinted genes, semen quality (including sperm count, morphology, and vitality) and male infertility is provided.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Sperm Count / Spermatogenesis / Spermatozoa / DNA Methylation / Semen Analysis / Infertility, Male Limits: Humans / Male Language: Chinese Journal: Chinese Journal of Medical Genetics Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Sperm Count / Spermatogenesis / Spermatozoa / DNA Methylation / Semen Analysis / Infertility, Male Limits: Humans / Male Language: Chinese Journal: Chinese Journal of Medical Genetics Year: 2021 Type: Article