Effect of pertussis vaccination on clinical manifestations of infants and young children with pertussis / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 138-142, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-879823
ABSTRACT
OBJECTIVE@#To study the effect of pertussis vaccination on the clinical manifestations of infants and young children with pertussis.@*METHODS@#A retrospective analysis was performed to investigate the differences in clinical manifestations and peripheral blood cell levels between pertussis children with different pertussis vaccination status.@*RESULTS@#A total of 1 083 children with pertussisat at age of < 3 years were enrolled, with 551 children in the unvaccinated group and 532 in the vaccinated group. Of all the children, 392 had an age of onset of < 3 months (372 were unvaccinated and 20 were vaccinated) and 691 children had an age of onset of ≥ 3 months (179 were unvaccinated and 512 were vaccinated). Compared with the vaccinated group, the unvaccinated group had a longer length of hospital stay and a higher incidence rate of respiratory failure (@*CONCLUSIONS@#Pertussis vaccination can reduce the incidence of severe pneumonia and respiratory failure and alleviate the severity of respiratory complications in infants and young children with pertussis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Whooping Cough
/
Incidence
/
Retrospective Studies
/
Vaccination
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Child
/
Child, preschool
/
Humans
/
Infant
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2021
Type:
Article
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