The Prognostic Factors for AML Children with CBFβ/MYH11 Positive / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 369-373, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-880083
ABSTRACT
OBJECTIVE@#To analyze the prognostic factors of AML children with CBFβ/MYH11 positive.@*METHODS@#Twenty-eight children with CBFβ/MYH11 positive treated in our hospital from May 2012 to June 2018 were selected, the clinical data and curative were analyzed and evaluated.@*RESULTS@#Five-year OS and 5-year EFS rate of CBFβ/MYH11 positive AML children was 76.8% and 64.0% efficacy, respectively. Univariate analysis results showed that the OS rate of CBFβ/MYH11 positive AML children with WBC<60.0×10@*CONCLUSION@#WBC level and XRCC-Thr241Met genotype at initial diagnosis are the major affecting factors for prognosis of AML children with CBFβ/MYH11 positive.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Leukemia, Myeloid, Acute
/
Oncogene Proteins, Fusion
/
Myosin Heavy Chains
/
Genotype
/
Chromosome Inversion
Type of study:
Prognostic study
Limits:
Child
/
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2021
Type:
Article
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