Animal models for study on rotator cuff injury / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 426-431, 2021.
Article
in English
| WPRIM
| ID: wpr-880677
ABSTRACT
Rotator cuff injuries are the most common cause of shoulder pain and dysfunction. Ideal animal shoulder models should have similar shoulder anatomy and function as human, and are able to replicate the microenvironment change after tendon injury. At present, a variety of animal models including rat, mouse, rabbit, sheep, canine, bovine, and primate have been used to study the mechanism of rotator cuff injury, effects of different repair techniques, and factors affecting tendon to bone healing. Although large animal models are more anatomically similar to humans, small animal models are more convenient in revealing the biological mechanism of rotator cuff injury and healing. Choosing appropriate animal models based on research objectives and establishing new small animal models play a critical role in revealing the mechanism of rotator cuff diseases and developing novel treating strategies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tendon Injuries
/
Wound Healing
/
Sheep
/
Rotator Cuff
/
Disease Models, Animal
/
Rotator Cuff Injuries
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Journal of Central South University(Medical Sciences)
Year:
2021
Type:
Article
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