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Overexpression of lncRNA MEG3 inhibits proliferation and invasion of glioblastoma U251 cells / 南方医科大学学报
Journal of Southern Medical University ; (12): 141-145, 2021.
Article in Chinese | WPRIM | ID: wpr-880841
ABSTRACT
OBJECTIVE@#To investigate the effects of overexpression of long noncoding RNA (lncRNA) MEG3 on the proliferation and invasion of glioblastoma U251 cells by suppressing the expression of hypoxia inducible factor 1@*METHODS@#The expression of lncRNA MEG3 and HIF1@*RESULTS@#The expression of MEG3 was significantly lower and HIF1@*CONCLUSIONS@#MEG3 overexpression inhibits the proliferation and invasion of U251 cells through suppressing the expression of HIF1
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Gene Expression Regulation, Neoplastic / Cell Movement / Apoptosis / Glioblastoma / MicroRNAs / Cell Line, Tumor / Cell Proliferation / RNA, Long Noncoding Limits: Humans Language: Chinese Journal: Journal of Southern Medical University Year: 2021 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Gene Expression Regulation, Neoplastic / Cell Movement / Apoptosis / Glioblastoma / MicroRNAs / Cell Line, Tumor / Cell Proliferation / RNA, Long Noncoding Limits: Humans Language: Chinese Journal: Journal of Southern Medical University Year: 2021 Type: Article