Dual-targeting nanovesicles enhance specificity to dynamic tumor cells
Acta Pharmaceutica Sinica B
;
(6): 2183-2197, 2020.
Article
in English
| WPRIM
| ID: wpr-881105
ABSTRACT
The dynamic or flowing tumor cells just as leukemia cells and circulating tumor cells face a microenvironment difference from the solid tumors, and the related targeting nanomedicines are rarely reported. The existence of fluidic shear stress in blood circulation seems not favorable for the binding of ligand modified nanodrugs with their target receptor. Namely, the binding feature is very essential in this case. Herein, we utilized HSPC, PEG-DSPE, cholesterol and two
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Acta Pharmaceutica Sinica B
Year:
2020
Type:
Article
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