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Current status of asthma control and influencing factors of occupational sensitizer-induced asthma / 中国职业医学
China Occupational Medicine ; (6): 716-721, 2020.
Article in Chinese | WPRIM | ID: wpr-881960
Responsible library: WPRO
ABSTRACT

OBJECTIVE:

To investigate the asthma control status of occupational sensitizer-induced asthma(OSIA) and explore the influencing factors.

METHODS:

A total of 50 OSIA patients were selected as study subjects by judgment sampling method. Asthma Control Test(ACT) and Asthma Quality of Life Questionnaire were used to investigate the asthma control status and the quality of life of patients. The fractional exhaled nitric oxide(FeNO) level, pulmonary function, peripheral blood eosinophil ratio(EOS%)and serum total immunoglobulin E(IgE) level of the patients were measured.

RESULTS:

Among the 50 cases of OSIA patients, 27(54.0%) cases were well controlled, and 23(46.0%) cases were non-fully controlled. The patients with allergic rhinitis, with no inhaled corticosteroids treatment and with poor compliance were risk factors of the non-fully controlled OSIA(all P<0.05). The scores of ACT and the quality of life, and the percentage of the first second forced expiratory volume(FEV_1%) decreased(all P<0.05), while the level of FeNO increased(P<0.05) in the non-fully controlled group compare with the well-controlled group. There was no statistical significance in EOS% and serum total IgE level between the two groups(both P>0.05).

CONCLUSION:

Allergic rhinitis, lack of inhaled corticosteroids treatment and poor compliance are the influencing factors that affect the control of OSIA. The combinational scores of ACT and quality of life, FeNO, FEV_1% and other indicators can reflect the status of OSIA and assess the level of asthma control, and help guiding OSIA diagnosis and treatment plans.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: China Occupational Medicine Year: 2020 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: China Occupational Medicine Year: 2020 Type: Article