Invasive infections related to anti-TNF-α therapy in pediatric inflammatory bowel disease / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 222-225, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-882329
ABSTRACT
Anti-tumor necrosis factor-α(anti-TNF-α)agents have been widely used in the treatment of inflammatory bowel disease(IBD)in children.Anti-TNF-α therapy can effectively induce and maintain disease remission, promote intestinal mucosal healing, and prevent long-term end-stage organ damage and growth retardation in pediatric IBD patient.Anti-TNF-α agents can significantly impair the human immune function, which may increase the infection risk of IBD children, including the infection of bacteria, viruses, fungi and mycobacteria.This study summarizes the current published literature regarding infections in pediatric patients with IBD receiving anti-TNF-α therapies, which can help to improve the cognition of pediatric medical staff on opportunistic infection of pediatric IBD patients following anti-TNF-α treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2021
Type:
Article
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