Progress of invasive pneumococcal disease in children / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 262-266, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-882338
ABSTRACT
Streptococcus pneumoniae is a common infectious pathogen in children and the main cause of death in children under 5 years of age.It can lead to non-invasive pneumococcal diseases such as sinusitis and otitis media, as well as invasive pneumococcal diseases(IPD) such as meningitis, sepsis and pneumonia.IPD is a serious infectious disease in children, with high morbidity and mortality.However, the incidence of IPD in children varies significantly among different ages, genders and regions.Penicillin used to be the first choice for the treatment of IPD.With the widespread use of antibiotics in clinical practice, the problem of drug resistance of Streptococcus pneumoniae continues to increase.The situation of antibiotic resistance of Streptococcus pneumoniae in China has been very serious, and some data show that the multiple drug resistance rate of Streptococcus pneumoniae is as high as 88.7%.As a result, streptococcus pneumococcal vaccines have emerged as the primary means of reducing the incidence of IPD, in addition, it is effective in reducing the spread of drug-resistant strains.This article reviews the epidemiological characteristics, pathogenesis, common invasive pneumococcal disease in children, laboratory diagnosis, treatment and prevention of IPD in children.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2021
Type:
Article
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