Clinical efficacy of pulsed radiofrequency in the treatment of knee osteoarthritis: a meta-analysis / 国际生物医学工程杂志

ABSTRACT

Objective:To evaluate the clinical efficacy of pulsed radio-frequency(PRF) for knee osteoarthritis(KOA) using Meta-analysis.Methods:The literature of controlled clinical studies on PRF in the treatment of KOA was retrieved, the retrieval databases included China Biomedical Literature Database, The Cochrane Library, PubMed, Web of Science, Medline, Embase, CNKI, Wanfang Database, VIP Database, CBM, EBSCO and Network database. The retrieval period was the time of inception to February 2021. The retrieved literature was screened, quality evaluated and data extracted by two researchers. Statistical analysis was performed using Review Manager 5.3 software.Results:A total of 8 studies were included, including 411 patients with KOA. The 200 patients in the trial group were underwent PRF treatment and the 211 patients in the control group were underwent conventional treatment. Meta-analysis results showed that the experimental group was superior to the control group in terms of knee VAS score, WOMAC score, Lysholm score and effective rate, and the differences were statistically significant (all P<0.05). Conclusions:PRF is more effective in treating KOA than conventional treatment. The quality of the literature research in this study that met the inclusion criteria was low, and a large number of high-quality studies are needed to evaluate the efficacy and safety of PRF treatment.