The ATP Level in the mPFC Mediates the Antidepressant Effect of Calorie Restriction / 神经科学通报·英文版
Neuroscience Bulletin
;
(6): 1303-1313, 2021.
Article
in English
| WPRIM
| ID: wpr-922625
ABSTRACT
Food deprivation can rescue obesity and overweight-induced mood disorders, and promote mood performance in normal subjects. Animal studies and clinical research have revealed the antidepressant-like effect of calorie restriction, but little is known about the mechanism of calorie restriction-induced mood modification. Previous studies have found that astrocytes modulate depressive-like behaviors. Inositol 1,4,5-trisphosphate receptor type 2 (IP3R2) is the predominant isoform in mediating astrocyte Ca
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Adenosine Triphosphate
/
Prefrontal Cortex
/
Mice, Knockout
/
Caloric Restriction
/
Antidepressive Agents
Limits:
Animals
Language:
English
Journal:
Neuroscience Bulletin
Year:
2021
Type:
Article
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