Progress of serum ferritin and its relationship with infection / 国际儿科学杂志

ABSTRACT

Ferritin is a polymeric protein composed of different ferritin subunits to store iron in the human body.It is involved in maintaining iron balance inside and outside the cell.Iron balance is disrupted by internal and external factors after infection.Studies have shown that ferritin is significantly elevated during infection and may affect the prognosis of the disease.However, due to insufficient understanding of ferritin, the study on ferritin is rarely in the clinic.This article aims to review the relationship between serum ferritin and infection from the aspects of the ferritin cycle, iron disturbance during infection, prediction, and prognosis of serum ferritin in infectious diseases, and provide a reference for further research.