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Prevalence of hyperkalemia and influencing factors in a rural population in Pinggu district of Beijing city / 中华肾脏病杂志
Chinese Journal of Nephrology ; (12): 289-295, 2022.
Article in Chinese | WPRIM | ID: wpr-933859
ABSTRACT

Objective:

To determine the epidemiology of hyperkalemia and influencing factors in a general population in Pinggu district of Beijing city.

Methods:

This study was a cross-sectional survey. The subjects were from the epidemiological survey population of chronic diseases in Pinggu district of Beijing city from March to May 2014. All participants completed a questionnaire, anthropological measurement, and venous blood samples collection to detect serum creatinine and potassium and so on. First void morning urine was collected to detect the albumin-creatinine ratio. Hyperkalemia and hypokalemia were defined as serum potassium level>5.0 mmol/L and≤3.5 mmol/L, respectively. Logistic regression analysis method was used to analyze the influencing factors of hyperkalemia.

Results:

Of the 10 252 people in this study, the prevalence of hyperkalemia was 6.17%(95% CI 5.70%-6.67%), the prevalence of hypokalemia was 0.61%(95% CI 0.47%-0.79%), and the prevalence of participants with serum potassium>5.5 mmol/L was 0.53%(95% CI 0.40%-0.69%). Multivariate logistic regression analysis results showed that males ( OR=1.269, 95% CI 1.074-1.498, P=0.005), diabetes ( OR=1.226, 95% CI 1.008-1.490, P=0.041), increased total cholesterol ( OR=1.219, 95% CI 1.119-1.329, P<0.001), and decreased estimated glomerular filtration rate ( OR=0.971, 95% CI 0.965-0.977, P<0.001) were significantly correlated with the increased risk of hyperkalemia. Usage of renin-angiotensin-aldosterone system inhibitors and diuretics were not found to be significantly associated with the risk of hyperkalemia ( OR=1.018, 95% CI 0.751-1.380, P=0.908; OR=0.638, 95% CI 0.229-1.781, P=0.391).

Conclusions:

The prevalence of HK in the general population is 6.17%. The male, decreased estimated glomerular filtration rate, diabetes, and increased total cholesterol are influencing factors of hyperkalemia.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prevalence study / Risk factors Language: Chinese Journal: Chinese Journal of Nephrology Year: 2022 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prevalence study / Risk factors Language: Chinese Journal: Chinese Journal of Nephrology Year: 2022 Type: Article