The Efficacy of Rh Phenotype Matched Blood Transfusion / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 865-869, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-939702
ABSTRACT
OBJECTIVE@#To analyze and evaluate the efficacy of Rh phenotype matched blood transfusion.@*METHODS@#The increasing of hemoglobin (Hb) and hemolysis tests in the patients treated by Rh matched red blood cells or not, as well as the first time unmatched transfusions and the unmatched transfusions happened again after a period (≥10 d) were retrospectively analyzed.@*RESULTS@#A total of 674 times transfusions in 120 patients were evaluated. The increasing of Hb in each unit was higher in the patients treated by Rh matched blood transfusion (vs unmatched) [(33.397±1.475) g/U vs (29.951±1.304) g/U, P=0.033], while the increasing of Hb at first time unmatched transfusion and the second time unmatched transfusion was not statistically different[ (28.942±2.083) g/U vs (30.686±1.737) g/U, P=0.589]. The level of lactate dehydrogenase were related to erythrocyte washing, irradiation, period of validity and the second time unmatched transtusion (all P<0.05); the levels of total bilirubin (TBil), direct bilirubin (DBil) and indirect bilirubin (IBil) between the first time unmatched transfusion and the second time unmatched transfusion were statistically different (all P<0.05).@*CONCLUSION@#For the patients need multiple blood transfusions, Rh phenotype matched blood transfusion can reduce the exposure to Rh allogenic antigens, improve the efficacy and ensure the safety of blood transfusion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Bilirubin
/
Blood Transfusion
/
Hemoglobins
/
Retrospective Studies
/
Erythrocyte Transfusion
Type of study:
Observational study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2022
Type:
Article
Similar
MEDLINE
...
LILACS
LIS