Comparison of effect-site concentration of remifentanil for tracheal intubation with the lightwand and laryngoscopy during propofol target-controlled infusion / 대한마취과학회지
Korean Journal of Anesthesiology
; : 393-397, 2011.
Article
in En
| WPRIM
| ID: wpr-9827
Responsible library:
WPRO
ABSTRACT
BACKGROUND: Target-controlled infusion (TCI) of propofol and remifentanil can provide satisfactory intubating conditions without a neuromuscular blocking agent. We compared the effect-site concentration of remifentanil required for intubation with the lightwand and the Macintosh laryngoscope during propofol TCI without a neuromuscular blocking agent in adult patients. METHODS: Forty-nine patients were randomly assigned to the lightwand group (n = 25) or the direct laryngoscope group (n = 24). Anesthesia was induced by propofol TCI with an effect-site concentration of 5.4 microg/ml. Two minutes after start of propofol TCI, remifentanil was administered at the predetermined effect-site concentration. The effect-site concentration of remifentanil was determined using Dixon's up-and-down method (0.5 ng/ml as a step size). The first patient in each group was tested at 4.5 ng/ml of remifentanil. Tracheal intubation was performed 2 min after the start of remifentanil TCI. Acceptable intubation was defined as an excellent or good intubating conditions. RESULTS: Using a modified Dixon's up and down method, the EC50 +/- SD of remifentanil in the lightwand and laryngoscope groups was 4.75 +/- 0.71 ng/ml and 5.08 +/- 0.52 ng/ml, respectively; there was no statistically significant difference between the groups (P = 0.373). CONCLUSIONS: The effect-site concentration of remifentanil for acceptable intubation with the lightwand and Macintosh laryngoscope in 50% of adults did not differ during propofol TCI without a neuromuscular blocking agent.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Piperidines
/
Propofol
/
Neuromuscular Blockade
/
Laryngoscopes
/
Intubation
/
Anesthesia
/
Laryngoscopy
Limits:
Adult
/
Humans
Language:
En
Journal:
Korean Journal of Anesthesiology
Year:
2011
Type:
Article