Pathological Complete Remission of Advanced Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombosis by Hepatic Arterial Infusion Chemotherapy
Gut and Liver
; : 266-269, 2010.
Article
in En
| WPRIM
| ID: wpr-199718
Responsible library:
WPRO
ABSTRACT
Cures for advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) are rare and difficult. We report a case of pathologically confirmed complete remission of HCC induced by hepatic arterial infusion chemotherapy (HAIC). A 45-year-old male patient had a massive HCC in the right lobe of the liver and tumor thrombus in the right and main portal veins. He achieved a partial response after two cycles of HAIC with 5-fluorouracil (750 mg/m2) and cisplatin (25 mg/m2). After the completion of six cycles he received a curative partial hepatectomy, and histopathology revealed complete necrosis without any viable tumor cell. He was in good health at a 4-month follow-up. These results suggest that this regimen is a promising therapeutic modality for the treatment of advanced HCC with PVTT.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Portal Vein
/
Thrombosis
/
Follow-Up Studies
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Cisplatin
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Carcinoma, Hepatocellular
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Fluorouracil
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Hepatectomy
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Liver
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Necrosis
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Humans
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Male
Language:
En
Journal:
Gut and Liver
Year:
2010
Type:
Article