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Salivary and Serum Biochemical Analysis from Patients with Chronic Renal Failure in Hemodialysis: A Cross-Sectional Study
Gonçalves, Ingrid Morgana Fernandes; Pessoa, Marília Barbosa; Leitão, Arlley de Sousa; Godoy, Gustavo Pina; Nonaka, Cassiano Francisco Weege; Alves, Pollianna Muniz.
Afiliación
  • Gonçalves, Ingrid Morgana Fernandes; State University of Paraíba. Post-graduate Program of Dentistry. Campina Grande. BR
  • Pessoa, Marília Barbosa; State University of Paraíba. Post-graduate Program of Dentistry. Campina Grande. BR
  • Leitão, Arlley de Sousa; State University of Paraíba. Post-graduate Program of Dentistry. Campina Grande. BR
  • Godoy, Gustavo Pina; Federal University of Pernambuco. Post-graduate Program of Dentistry. Recife. BR
  • Nonaka, Cassiano Francisco Weege; State University of Paraíba. Post-graduate Program of Dentistry. Campina Grande. BR
  • Alves, Pollianna Muniz; State University of Paraíba. Post-graduate Program of Dentistry. Campina Grande. BR
Article en En | LILACS, BBO | ID: biblio-1287504
Biblioteca responsable: BR1264.1
ABSTRACT
ABSTRACT

Objective:

To compare salivary and serum biochemical levels in patients with chronic renal failure undergoing hemodialysis. Material and

Methods:

The sample was composed of 57 patients treated in Hemodialysis Reference Centers, from a state of Northeastern Brazilian, with age ≥21 years old with at least 3 months of hemodialysis treatment time. Serum data were obtained from records. Unstimulated and stimulated saliva were collected. Flow rate (mL/min) was measured. Spectrophotometry was performed for the measurement of salivary levels of calcium (570 nm), urea (340 nm), and creatinine (510 nm). Statistical analysis used Mann Whitney and Kruskal-Wallis tests (p<0.05).

Results:

Unstimulated and stimulated salivary flow rates were 0.43 mL/min and 1.69 mL/min, respectively. There was significant difference (p<0.001) of levels of calcium (5.41 mg/dL and 9.70 mg/dL), urea (118.03 mg/dL and 183.22 mg/dL) and creatinine (0.59 mg/dL and 9.20 mg/dL) between saliva and serum, respectively. Concerning the time of hemodialysis, salivary and serum calcium not exhibited significant association; however, serum urea (p=0.012) and serum creatinine (p=0.025) showed significant association to the time of hemodialysis.

Conclusion:

Salivary biochemical levels of urea, creatinine and calcium can indicate the presence of a possible chronic renal failure and the saliva demonstrated to be a potential auxiliary biofluid for clinical monitoring renal alterations.
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Texto completo: 1 Índice: LILACS Asunto principal: Saliva / Espectrofotometría / Diálisis Renal / Creatinina / Insuficiencia Renal Crónica Tipo de estudio: Evaluation_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: ODONTOLOGIA Año: 2021 Tipo del documento: Article

Texto completo: 1 Índice: LILACS Asunto principal: Saliva / Espectrofotometría / Diálisis Renal / Creatinina / Insuficiencia Renal Crónica Tipo de estudio: Evaluation_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male País/Región como asunto: America do sul / Brasil Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Asunto de la revista: ODONTOLOGIA Año: 2021 Tipo del documento: Article