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Factors associated with surgical resection in patients with Crohn's disease: long-term evaluation
Ferreira, Sandro da Costa; Aprile, Lílian Rose Otoboni; Parra, Rogério Serafim; Feitosa, Marley Ribeiro; Castro, Patrícia Picardi Morais de; Perdoná, Gleici de Castro da Silva; Feres, Omar; Rocha, José Joaquim Ribeiro da; Troncon, Luiz Ernesto de Almeida.
Afiliación
  • Ferreira, Sandro da Costa; Universidade de São Paulo. Medical School. Department of Medicine. Ribeirão Preto. BR
  • Aprile, Lílian Rose Otoboni; Universidade de São Paulo. Medical School. Department of Medicine. Ribeirão Preto. BR
  • Parra, Rogério Serafim; Universidade de São Paulo. Medical School. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Feitosa, Marley Ribeiro; Universidade de São Paulo. Medical School. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Castro, Patrícia Picardi Morais de; Universidade de São Paulo. Medical School. Department of Social Medicine. Ribeirão Preto. BR
  • Perdoná, Gleici de Castro da Silva; Universidade de São Paulo. Medical School. Department of Social Medicine. Ribeirão Preto. BR
  • Feres, Omar; Universidade de São Paulo. Medical School. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Rocha, José Joaquim Ribeiro da; Universidade de São Paulo. Medical School. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Troncon, Luiz Ernesto de Almeida; Universidade de São Paulo. Medical School. Department of Medicine. Ribeirão Preto. BR
Acta cir. bras ; Acta cir. bras;39: e391924, 2024. tab, graf
Article en En | LILACS, VETINDEX | ID: biblio-1556668
Biblioteca responsable: BR68.1
Ubicación: BR68.1
ABSTRACT

Purpose:

To evaluate patient characteristics and factors associated with surgical resection in patients with Crohn's disease (CD).

Methods:

An analysis was performed on data from 295 patients with CD in follow-up from 2001 to 2018. Medical record data comprised age, gender, location, behavior and duration of the CD, smoking, and extraintestinal manifestation. Patients were divided into two groups according to the presence or absence of surgical resection.

Results:

Out of the 295 patients with CD, 155 underwent surgical resection (53.2% male, mean age 43.88 ± 14.35 years). The main indications for surgery were stenosis (44.5%), clinical intractability (15.5%), and intra-abdominal fistulas (15.5%). Smoking (p < 0.001), longer CD duration (p < 0.0001), ileo-colonic location (p = 0.003), stenosing behavior (p < 0.0001), and fistulizing behavior (p < 0.0001) were significantly associated with surgical resection. Initial use of biological was significantly more frequent in the group of patients without surgical resection (p < 0.001).

Conclusions:

Patients with CD still frequently need surgical treatment. Smoking (current or past), longer disease time, stenosing and fistulizing behavior, and ileo-colonic localization in CD patients were associated with a higher risk of surgery. Awareness about factors associated with unfavorable outcome allows such patients to be treated more appropriately.
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Texto completo: 1 Índice: LILACS Asunto principal: Enfermedades Inflamatorias del Intestino / Enfermedad de Crohn / Factores de Riesgo Límite: Humans Idioma: En Revista: Acta cir. bras Asunto de la revista: Cirurgia Geral / Procedimentos Cir£rgicos Operat¢rios Año: 2024 Tipo del documento: Article

Texto completo: 1 Índice: LILACS Asunto principal: Enfermedades Inflamatorias del Intestino / Enfermedad de Crohn / Factores de Riesgo Límite: Humans Idioma: En Revista: Acta cir. bras Asunto de la revista: Cirurgia Geral / Procedimentos Cir£rgicos Operat¢rios Año: 2024 Tipo del documento: Article