What do Cochrane systematic reviews say about the use of cannabinoids in clinical practice?
São Paulo med. j
; 136(5): 472-478, Sept.-Oct. 2018. tab
Article
en En
| LILACS
| ID: biblio-979377
Biblioteca responsable:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND:
The therapeutic effects of cannabinoid compounds have been the center of many investigations. This study provides a synthesis on all Cochrane systematic reviews (SRs) that assessed the use of cannabinoids as a therapeutic approach. DESIGN ANDSETTING:
Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).METHODS:
A broad search was conducted in the Cochrane Database of Systematic Reviews to retrieve any Cochrane SRs that assessed the efficacy and safety of cannabinoids as a therapeutic approach. The results and key characteristics of all reviews included were summarized and discussed.RESULTS:
Eight SRs were included. They assessed the use of cannabinoids for the following types of conditions neurological (two SRs), psychiatric (two SRs), rheumatological (one SR), infectious (one SR) and oncological (two SRs). There was moderate-quality evidence showing that the use of cannabinoids reduced nausea and vomiting among adults, compared with placebo. Additionally, there was moderate-quality evidence showing that there was no difference between cannabinoids and prochlorperazine regarding the number of participants who reported vomiting, in this same population.CONCLUSIONS:
This review identified eight Cochrane systematic reviews that provided evidence of unknown to moderate quality regarding the use of cannabinoids as a therapeutic intervention. Further studies are still imperative for solid conclusions to be reached regarding practical recommendations.Palabras clave
Texto completo:
1
Índice:
LILACS
Asunto principal:
Cannabinoides
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Revisiones Sistemáticas como Asunto
Tipo de estudio:
Clinical_trials
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Guideline
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Prognostic_studies
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Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
São Paulo med. j
Asunto de la revista:
Cirurgia Geral
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Cincia
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Ginecologia
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MEDICINA
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Medicina Interna
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Obstetr¡cia
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Pediatria
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Sa£de Mental
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Sa£de P£blica
Año:
2018
Tipo del documento:
Article