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Acro-osteolysis and mononeuritis multiplex as a presenting symptom of systemic angiitis of Wegener's type.
Indian J Med Sci ; 2007 Apr; 61(4): 212-5
Article en En | IMSEAR | ID: sea-66613
Wegener's granulomatosis is a multisystem disorder involving small- and medium-sized vessels, leading to granuloma formation and involvement of upper and lower respiratory tract with or without glomerulonephritis. However, limited forms of angiitis and granulomatosis of the Wegener's type with oligosymptomatic and atypical site involvement are known to occur. We present here a rare case of limited form of angiitis and granulomatosis of Wegener's type who presented sequentially with spontaneous resorption of digits with acro-osteolysis and mononeuritis multiplex over a period of 10 months. His vasculitic workup revealed high proteinase 3 antibodies (c-ANCA) titers and an almost asymptomatic lung involvement, detected on high-resolution computed tomography of chest. The patient was aggressively treated with immunosuppressive therapy, following which he showed good improvement.
Asunto(s)
Texto completo: 1 Índice: IMSEAR Asunto principal: Vasculitis / Humanos / Masculino / Granulomatosis con Poliangitis / Anticuerpos Anticitoplasma de Neutrófilos / Mononeuropatías / Acroosteólisis / Dedos / Inmunosupresores / Pulmón Idioma: En Revista: Indian J Med Sci Año: 2007 Tipo del documento: Article
Texto completo: 1 Índice: IMSEAR Asunto principal: Vasculitis / Humanos / Masculino / Granulomatosis con Poliangitis / Anticuerpos Anticitoplasma de Neutrófilos / Mononeuropatías / Acroosteólisis / Dedos / Inmunosupresores / Pulmón Idioma: En Revista: Indian J Med Sci Año: 2007 Tipo del documento: Article