Effect of NMDA receptor blocker in relieving HIV-1/gp120 induced learning and memory disorder in rats and its mechanism / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 1149-1156, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1013791
Biblioteca responsable:
WPRO
ABSTRACT
Aim:
To investigate the alleviating effect of NMDA receptor blocking on learning and memory impairment induced by gp120 in rats and its mechanism.Methods:
(1 ) Thirty-two SD rats were randomly divided into control group, sham operation group, gpl20 group, and gp120 + Memantine group. Except for the control group, the other groups underwent a bilateral hippocampal injection to establish the model of learning and memory impairment in rats. Memantine (10 mg • kg
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
2023
Tipo del documento:
Article