Mechanisms and potential applications of extracellular vesicles in bipolar disorder / 中国神经精神疾病杂志
Chinese Journal of Nervous and Mental Diseases
; (12): 631-635, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1024915
Biblioteca responsable:
WPRO
ABSTRACT
The pathogenesis of bipolar disorder(BD)is unknown,and objective biomarkers with clinical guidance are lacking.Extracellular vesicles(EV)are lipid bilayer-enclosed vesicles that carry cargo from originating cells,influencing the processes of recipient cells.They are capable of crossing the blood-brain barrier and reflecting the ongoing processes in the central nervous system.Compelling data indicates that EV could mediate BD pathophysiological processes such as neurocognitive impairment,neuroinflammatory diffusion,and metabolic dysfunction.Therefore,EV has the potential to become a reliable biomarker and therapy for BD,providing new ideas for revealing the pathogenesis and clinical diagnosis and treatment of BD.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Nervous and Mental Diseases
Año:
2023
Tipo del documento:
Article