Progress in depression research using genetically modified animal models / 中国实验动物学报
Acta Laboratorium Animalis Scientia Sinica
; (6): 1610-1616, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1025033
Biblioteca responsable:
WPRO
ABSTRACT
Depression is a complex mental disease with polygenic inheritance and a high incidence.Our understanding of the clinical manifestations and pathogenesis of depression has recently improved.Continuous progress in gene-editing technologies has increased the construction efficiency and reduced the cost of gene-knockout animals,leading to their increasing use in the fields of basic research and drug development for depression and providing a powerful tool for revealing the pathogenesis of depression.In this review,we summarize recent progress in understanding the roles and mechanisms of candidate genes in depression using knockout model mice.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Acta Laboratorium Animalis Scientia Sinica
Año:
2023
Tipo del documento:
Article