Risk Factors for Mortality in Patients with Serratia marcescens Bacteremia
Yonsei Medical Journal
; : 348-354, 2015.
Article
en En
| WPRIM
| ID: wpr-210032
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE:
Over the last 30 years, Serratia marcescens (S. marcescens) has emerged as an important pathogen, and a common cause of nosocomial infections. The aim of this study was to identify risk factors associated with mortality in patients with S. marcescens bacteremia. MATERIALS ANDMETHODS:
We performed a retrospective cohort study of 98 patients who had one or more blood cultures positive for S. marcescens between January 2006 and December 2012 in a tertiary care hospital in Seoul, South Korea. Multiple risk factors were compared with association with 28-day all-cause mortality.RESULTS:
The 28-day mortality was 22.4% (22/98 episodes). In a univariate analysis, the onset of bacteremia during the intensive care unit stay (p=0.020), serum albumin level (p=0.011), serum C-reactive protein level (p=0.041), presence of indwelling urinary catheter (p=0.023), and Sequential Oran Failure Assessment (SOFA) score at the onset of bacteremia (p<0.001) were significantly different between patients in the fatal and non-fatal groups. In a multivariate analysis, lower serum albumin level and an elevated SOFA score were independently associated with 28-day mortality [adjusted odds ratio (OR) 0.206, 95% confidential interval (CI) 0.044-0.960, p=0.040, and adjusted OR 1.474, 95% CI 1.200-1.810, p<0.001, respectively].CONCLUSION:
Lower serum albumin level and an elevated SOFA score were significantly associated with adverse outcomes in patients with S. marcescens bacteremia.Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Serratia marcescens
/
Factores de Tiempo
/
Índice de Severidad de la Enfermedad
/
Infección Hospitalaria
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Resultado del Tratamiento
/
Infecciones por Serratia
/
Bacteriemia
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Yonsei Medical Journal
Año:
2015
Tipo del documento:
Article