Genotype of human calicivirus from infants with diarrhea in Guangzhou city in 2001 / 中华儿科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To understand the characteristics of human calicivirus (HuCV) infection in infants with diarrhea in Guangzhou city and to study genotype of the virus.</p><p><b>METHODS</b>The authors collected fecal specimens from 22 children with acute nonbacterial gastroenteritis from November to December, 2001. HuCV was detected from the specimens by RT-PCR. The PCR products were cloned into the PMD18-T cloning vector and sequenced.</p><p><b>RESULTS</b>HCV was detected from the specimens of 2 cases (9%, 2/22). The nucleotide sequence analysis revealed that the virus strains belonged to genotype 2 of Norwalk-like viruses.</p><p><b>CONCLUSION</b>HuCV is one of the pathogens causing diarrhea in infants and young children in Guangzhou area. HuCV infection occurred sporadically in autumn and winter.</p>