A new model for survival assessment based on the Chinese liver transplantation patients with hepatocellular carcinoma / 中华外科杂志
Chinese Journal of Surgery
; (12): 1023-1026, 2007.
Article
en Zh
| WPRIM
| ID: wpr-340868
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To establish a new model for liver transplantation recipients with hepatocellular carcinoma (HCC) and validate the feasibility of it.</p><p><b>METHODS</b>From February 1999 to June 2005, clinical data of 130 liver cancer patients who accepted liver transplantation were collected. Screening the pretransplant factors correlated with post-transplant survival using COX proportional-hazards regression, and establishing the assessment model. Finally, the area under the receiver operating characteristic curve (AUC ROC) were used to compare the validity of the new model with MELD.</p><p><b>RESULTS</b>Screened by the COX model, serum concentrations of alkaline phosphatase, alphafetoprotein, sodium and the number of tumor nodule were significantly related with post-transplant survival. The new model with these four variables had greater ability to assess post-transplant recipients' outcomes, however, the MELD had not evaluation capacity.</p><p><b>CONCLUSION</b>The established new model has a better ability to assess the risk of post-transplant mortality.</p>
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Sodio
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Cirugía General
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Sangre
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Alfa-Fetoproteínas
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Modelos de Riesgos Proporcionales
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Análisis de Supervivencia
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China
/
Estudios de Factibilidad
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Reproducibilidad de los Resultados
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Trasplante de Hígado
Tipo de estudio:
Prognostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Año:
2007
Tipo del documento:
Article