Qualitative analysis of the main chemical constituents of shuanghuanglian injection powder and their origin by HPLC-ESI/MS/MS spectrometry / 药学学报
Acta Pharmaceutica Sinica
; (12): 1391-1396, 2009.
Article
en Zh
| WPRIM
| ID: wpr-344065
Biblioteca responsable:
WPRO
ABSTRACT
This paper is to report the analysis of the main chemical constituents of Shuanghuanglian injection powder and determination of their origin. The sample solution was analyzed by a Zorbax C18 column with a gradient mobile phase comprised of methanol and 0.25% acetic acid solution. Both UV and electrospray ionization mass spectrometry detector were used simultaneously, -Q1-scan detection mode was evaluated for the identification of the LC peaks. To analyze the mass spectrum of every LC peaks, 43 molecular mass from the ion chromatogram of Shuanghuanglian injection powder were identified and among them, structure of 20 compounds were elucidated, and the data were sorted to the three component herbs, separately.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Plantas Medicinales
/
Polvos
/
Flavonoides
/
Medicamentos Herbarios Chinos
/
Química
/
Ácido Clorogénico
/
Cromatografía Líquida de Alta Presión
/
Espectrometría de Masa por Ionización de Electrospray
/
Lonicera
/
Scutellaria
Tipo de estudio:
Qualitative_research
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Año:
2009
Tipo del documento:
Article