Study on application of activated carbon in paclitaxel injection / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To inspect the effect of activated carbon with different dosage and temperature on quality of paclitaxel injection.</p><p><b>METHOD</b>Determinations in WS1-(X-026)-2001Z-paclitaxel injection were refered to compare the effect of different dosage and temperature for activated carbon on the taxol content, related material, clarity and bacterial endotoxin.</p><p><b>RESULT</b>When used with 0.25% and 35 degrees C, activated carbon will ensure the quality of paclitaxel injection.</p><p><b>CONCLUSION</b>0.25% and 35 degrees C are the best condition when activated carbon is used in paclitaxel injection.</p>