Studies on chemical constituents in spikes of Schizonepeta tenuifolia / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents in the spikes of Schizonepeta tenuifolia.</p><p><b>METHOD</b>Compounds were isolated and purified with silica gel, ODS and Sephadex LH-20 gel column chromatography, and their structures were determined by using spectroscopic analysis including MS and NMR.</p><p><b>RESULT</b>Nine compounds were isolated and identified as 5, 7-dihydroxy-6, 4'-dimethoxyflavone (1), 5, 7-dihydroxy-6, 3', 4'-trimethoxyflavone (2), ursolic acid (3), 3-hydroxy-4(8)-ene-p-menthane-3(9)-lactone (4), 5, 7, 4'-trihydroxyflavone (5), 5, 4'-dihydroxy-7-methoxyflavone (6), hesperidin (7), luteolin (8) and daucesterol (9).</p><p><b>CONCLUSION</b>Compounds 1, 2, 6 were first obtained from the spikes of S. tenuifolia.</p>