Fibrillary glomerulonephritis combined with chronic inflammatory demyelinating polyneuropathy
Kidney Research and Clinical Practice
; : 117-119, 2015.
Article
en En
| WPRIM
| ID: wpr-50605
Biblioteca responsable:
WPRO
ABSTRACT
A 58-yr-old man presented with leg edema and subacute weakness of his bilateral lower extremities. Urinary and serum immunoelectrophoresis revealed the presence of lambda-type Bence Jones proteins. He was ultimately diagnosed with monoclonal gammopathy of undetermined significance (MGUS). A renal biopsy specimen showed fibrillary glomerulonephritis (FGN), which was randomly arranged as 12-20 m nonbranching fibrils in the basement membranes. Immunofluorescence studies were negative for immunoglobulin (Ig)G, IgM, IgA, C3, and kappa light chains in the capillary walls and mesangial areas. A Congo red stain for amyloid was negative. Electromyography and nerve conduction velocity examinations results were compatible with the presence of demyelinating polyneuropathy. This case showed a rare combination of FGN, without Ig deposition, and MGUS combined with chronic inflammatory demyelinating polyneuropathy (CIDP).
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Paraproteinemias
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Polineuropatías
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Membrana Basal
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Biopsia
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Gammopatía Monoclonal de Relevancia Indeterminada
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Proteína de Bence Jones
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Inmunoglobulina A
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Inmunoglobulina M
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Inmunoglobulinas
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Capilares
Idioma:
En
Revista:
Kidney Research and Clinical Practice
Año:
2015
Tipo del documento:
Article