Effects of Foot-shock, Cold and Scalding on Dynorphin B Neurons in Rat Hypothalamus / 第二军医大学学报

ABSTRACT

With the immunocytochemical PAP-floating method we studied the effects of foot-shock, cold and scalding on Dynorphin B (Dyn B) neurons in the rat hypothalamus. The results showed that in the foot-shock condition, the anteroposterior diameter of PVH (paraventricular nucleus of hypothalamus) and PVM (paraventricular nucleus of hypothalamus, medial part) with Dyn B neurons, the total number of Dyn B neurons in PVH and the number of thick fibers in SON (supraoptic nucleus) and PVH were increased obviously; in the cold condition there was declining tendency of the total number of Dyn B neurons in PVH; and in the scalding condition the staining density of median eminence was much deeper than that in normal condition. These results imply that Dyn B neurons in the rat hypothalamus is associated with these stress responses.