Relationship between Renal Nitric Oxide and Glomerular Hyper filtration in Experimental Diabetic Rats / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)1986.
Article
en Zh
| WPRIM
| ID: wpr-638374
Biblioteca responsable:
WPRO
ABSTRACT
Objective To explore the mobile changes of nitric oxide(NO) and the relationship between nitric oxide and glomerular hyperfiltration in experimental diabetic rats.Methods Experimental diabetes mellitus(DM) was induced in rats with streptozotocin(STZ).The levels of NO and NOS in renal tissue homogenate were assayed after establishment of diabetesat the 4 th,8 th,12 th week.At the same time, renal morphology in diabetic rats was examined by light microscope and image of computer.Results The contents of NO and NOS in renal homegenates were evidently increased at 4 th week,and decreased gradually from 8 th week(P
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Año:
1986
Tipo del documento:
Article