Immunologic function of palatine tonsil B lymphocyte / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 311-315, 2009.
Article
en Zh
| WPRIM
| ID: wpr-748237
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE@#To study cellular immune function of palatine tonsil B lymph cell.@*METHOD@#The phenotype of palatine tonsil cells (PTC) and that of peripheral blood mononuclear cell (PBMC) were compared using fluorescence staining and flow cytometry (FCM) analysis, then immunomagnetic beads were used to separate CD3- cell in PTC and PBMC. The proliferation function of CD3- lymph cell of PTC and PBMC was tested after stimulated by CD20mAb.@*RESULT@#FCM analysis founding that 71.2% PTC express CD20 with higher mean fluorescence intensity, MFI, compared to the 15.5% in PBMC. There's no significant difference between the proliferation of PTC and PBMC B lymph cell.@*CONCLUSION@#CD20 expression is different in PTC and PBMC, but corresponding function is still unknown.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Tonsila Palatina
/
Linfocitos B
/
Antígenos CD20
/
Biología Celular
/
Alergia e Inmunología
/
Citometría de Flujo
/
Metabolismo
Límite:
Adult
/
Humans
Idioma:
Zh
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Año:
2009
Tipo del documento:
Article